This I suspect will mirror the effects of Endocrine disruptors. The Pill being only one of the 250 + known substances (endocrine disruptors) that enter the rivers. Ergo rivers that run through centers of population will be where the fish will be affected most.
And again only the effects on fish have been looked at and not the upper and lower life zooplankton and the impacts on them.
Take all upper life, fish predators, if the same effects are mirrored in them, and there's no reason to think they are not, then the same effects as is being suggested for fish will be happening to them.
Supercharged Predators perhaps???????
If the same effects happen with the zooplankton, then you'd perhaps have supercharge zooplankton.
It could then be argued little would change, other than a stepchange to superchargedness in aquatic life. Most unlikely I'll grant you, but watch the manufactures of the drugs try to advance this arguement
mg:
It's big, big money for them so they'll kick and scream all the way to regulation on the products.